Ukushintshwa Kwevalve Yomtholampilo Ye-Mitral Okokuqala Okuphumelelayo

Isiguli ngowesifazane oneminyaka engu-74 ubudala osanda kulaliswa esibhedlela ngenxa yokwehluleka kwenhliziyo kwesokunxele okuphindaphindiwe, kanye ne-atrial fibrillation eqhubekayo, umfutho wegazi ophezulu, isifo sikashukela nezinye izifo zezokwelapha. Ukusebenza kuhambe kahle ngokuma okuhle nomphumela omuhle wangemva kwenqubo. I-mitral valve regurgitation yaqedwa ngokushesha ngemva kwenqubo ngaphandle kokuvinjelwa kwe-LVOT. Isiguli besilulama kahle, futhi sasuswa egunjini labagula kakhulu (ICU) sayiswa ewodini elijwayelekile ngakusasa ngokusebenza okuvamile kwenhliziyo. Ukhishwe esibhedlela ngo-December 30, 2021. Le nqubo eyimpumelelo yabeka isisekelo esiqinile sezinkinga zomtholampilo zesikhathi esizayo zohlelo lwe-Peijia's HighLife TSMVR e-China.              

"Idizayini eyingqayizivele 'yeValve-in-Ring' iyenza ifanelekele uhla olubanzi lwe-mitral valve anatomy." kusho uSolwazi Mao Chen. "Iziguli eziningi ngeke zidinge ukuvalwa kwesici se-atrial septal ngemuva kokubhobozwa kwe-transseptal nge-30F yokulethwa kwe-catheter, futhi amathuba okuba nezinkinga zemithambo aphansi kakhulu. Inqubo yenziwa ngaphansi kwe-DSA ejwayelekile ngokubambisana ne-echocardiogram, ezogqugquzela ukwamukelwa kwalobu buchwepheshe. Ngiyethemba ukuthi lobu buchwepheshe bungasetshenziswa ekusetshenzisweni okwengeziwe komtholampilo esikhathini esizayo esiseduze ukuze kuzuze iziguli ezine-mitral regurgitation. "

Ubuchwepheshe be-HighLife bunikeza izici eziyingqayizivele zokwelapha ukungasebenzi kahle kwe-mitral valve

I-Transcatheter Mitral Valve Replacement (“TMVR”) ibilokhu ithrenda emkhakheni wokwelashwa okungenelelayo kwezifo zenhliziyo ezihlelekile. Izifundo zokuhlola zakuqala ziye zafakazela ukuphepha nokusebenza kwalobu buchwepheshe. I-TMVR ifanele izici ezibanzi ze-anatomical ze-mitral regurgitation (“MR”). Kunganciphisa noma kuqede ngokuphelele ukuphindaphinda futhi imiphumela yesiguli ivame ukusimama. Ngaphezu kwalokho, i-TMVR ayihlaseli kancane futhi ingenziwa ezigulini esezikhulile noma ezisengozini enkulu uma iqhathaniswa nokushintshwa kokuhlinzwa.

Kodwa-ke, inkambu ye-Mitral Valve Replacement isabhekene nezinkinga eziningi zobuchwepheshe, okuhlanganisa ukufinyelela endaweni okuhloswe kuyo, ukubambelela kanye nobungozi bokuvuza kwe-paravalvular (“PVL”) nokuvinjwa kwe-LVOT. Izindlela eziningi ezikhona zingama-transapical noma i-anchoring zisebenzisa amandla e-radial. I-Transapical TMVR ingaholela ekubeni buthaka komsipha wodonga lwe-ventricular yesokunxele noma ngisho nokuzenzakalelayo ekushayweni kwe-ventricular yesokunxele ngenxa yokusikwa ngokuhlinzwa. Ukubambelela kwe-TMVR ngamandla e-radial kungaholela kusayizi omkhulu wevalvu nobunzima ekuletheni, okungase kuholele ekulungisweni kabusha kwe-ventricular reverse kwesokunxele. Uhlelo lwe-HighLife TSMVR lusebenzisa umqondo oyingqayizivele othi “Valve-in-Ring” ongabhekana kangcono nalezi zinselele. Lolu hlelo luhlukanisa i-valve neringi yayo yokunamathisela futhi ihambise izingxenye ezimbili ngomthambo wesifazane kanye nomthambo wesifazane ngokulandelana.

Kuyinqubo elula enezinyathelo ezintathu. Okokuqala, iluphu yocingo engumhlahlandlela ibekwa eduze kwamapheshana e-valve omdabu esiguli kanye ne-chordae. Okwesibili, indandatho yokunamathisela ifakwe. Ekugcineni, i-valve ye-bovine pericardial eyandayo ikhishwa ngokufinyelela kwe-transseptal. Ivalvu edilivwe iqiniswa ngokuxhumana bese ifinyelela endaweni yokulinganisa ngeringi emiswe ngaphambilini. Lokhu kuvumela i-valve ukuthi ihlale endaweni ezinzile ngaphandle kokulimaza izicubu zokuqala. Inqubo ilula uma kuqhathaniswa njengoba isistimu izicabangela yona futhi iyaziqondanisa. Idizayini yesistimu isiza ukunciphisa ubungozi bokuvuza kwe-paravalvular futhi yehlise ngempumelelo usayizi we-catheter. Inqubo ingaqedwa ngempumelelo kusetshenziswa ukwesekwa kwe-teleproctoring.

I-Peijia Medical ibonise amandla ayo ekusebenzisaneni namazwe ngamazwe kanye nobuchwepheshe bezobuchwepheshe

NgoZibandlela wezi-2020, i-Peijia Medical yangena esivumelwaneni selayisense ne-HighLife SAS, inkampani yamathuluzi ezokwelapha ezinze e-France, ngemva kwalokho i-HighLife SAS inikeze i-Peijia Medical ilayisense elikhethekile lokuthuthukisa, ukwenza nokudayisa imikhiqizo ethile yobunikazi ye-TMVR esifundeni sase-Greater China. Lokhu kudluliswa kobuchwepheshe kwaqedwa ngekota yesithathu ka-2021. Ukukhiqizwa kwasendaweni okunezindinganiso zekhwalithi ephezulu e-China sekusungulwe: umshini we-HighLife okhiqizwe i-Peijia Medical uphumelele zonke izivivinyo zokusebenza okubonisa ukuthi zilingana kakhulu ne-HighLife SAS. Kusukela ekuqaleni kokudluliswa kobuchwepheshe kuya ekufakweni kokuqala ocwaningweni lwezokwelapha e-China, i-Peijia Medical yathatha isikhathi esingaphansi konyaka owodwa ukuqedela inqubo eyabonisa amandla ayo ekusebenzisaneni namazwe ngamazwe kanye nobuchwepheshe bezobuchwepheshe.

Ukuze kusheshiswe ukusetshenziswa kwalobu buchwepheshe obuhamba phambili emhlabeni ukuze kuzuze iziguli ze-MR e-China, abeluleki be-Peijia Medical, uSolwazi Nicolo Piazza kanye noSolwazi uJean Buithieu baseMcGill University Medical Centre eCanada, kanye nochwepheshe bezobuchwepheshe be-HighLife SAS basebenze eduze noPeijia. Ezokwelapha zokulungiselela lolu cwaningo lomtholampilo. Izikhathi zokuqeqesha eziningana ezihilela ukuhlotshaniswa kwedivayisi nokusebenza komtholampilo zenziwa futhi Odokotela benhliziyo e-China nabo babambe iqhaza ngenkuthalo kule nqubo yokuqinisekisa ukufakwa ngempumelelo.

UDkt. Nicolo Piazza ucabange kakhulu ngalokhu kubambisana nokufakelwa ngempumelelo. “Ngijabule kakhulu futhi ngizizwa ngihloniphekile ukweseka uSolwazi Mao Chen nethimba lakhe ukude ukuze benze inqubo ye-HighLife TSMVR futhi babelane ngolwazi lwami lobuchwepheshe. Ngiphinde ngamangazwa indlela esezingeni eliphezulu kanye nokubambisana okuthule kukaSolwazi Mao Chen kanye neqembu. Ngijabule kakhulu ngokufakelwa ngempumelelo kohlelo lokuqala lwe-TSMVR e-Asia. Bengikholelwa ukuthi uhlelo lwe-HighLife TSMVR lungazuzisa iziguli eziningi esikhathini esizayo, futhi ngibheke phambili ekuthuthukisweni okunamandla emkhakheni we-mitral valve interventional therapy.”

Ukunamathela embonweni wayo othi “Ukuzinikela Enhliziyweni, Ukuhlonipha Ukuphila”, i-Peijia Medical ilwela ukuthuthukisa ikhwalithi yempilo yeziguli ngokuhlola kobuchwepheshe nokuphikelela okusha. “Sibone ucwaningo olwengeziwe mayelana nendlela ubuchwepheshe be-TMVR obuqondisa ngayo izinselelo ezivela ku-anatomy eyinkimbinkimbi ye-mitral valve kanye nobukhulu besifo. Le mizamo eqhubekayo ibonisa ukubaluleka kokwelashwa kwe-TMVR,” kusho uDkt. Michael Zhang Yi, uSihlalo kanye ne-CEO ye-Peijia Medical. “Nakuba indlela ye-transseptal iyindlela ethandwayo futhi iphumelela ngezindlela eziningi, iningi lobuchwepheshe obukhona be-TMVR lusasebenzisa indlela ye-transapical. I-HighLife SAS ingumholi womhlaba kubuchwepheshe be-TSMVR, enemiphumela ethembisayo yesilingo somtholampilo eshicilelwe ku-TCT 2021 kanye ne-PCR London Valves 2021. Sibonga uSolwazi Mao Chen kanye noSolwazi Nicolo Piazza ngokubambisana kwabo ekufakweni kokuqala kwe-Peijia's HighLife System, ukufakelwa ngempumelelo iphinde yaqinisa ukuzethemba kwethu ekwelapheni izifo ze-mitral valve ngobuchwepheshe bokungenelela obungenelela kancane. IPeijia Medical izoqhubeka nokuzinikela kwethu ekusunguleni izinto ezintsha, ngethemba lokuthi iziguli eziningi zaseShayina ezihlushwa isifo i-mitral valve zingazuza kulokhu kuthuthuka kwezobuchwepheshe. "

Isistimu ye-Peijia's HighLife TSMVR imele ukwelashwa kwe-mitral valve interventional yesimanjemanje, okuzothuthukisa kakhulu izinga lempilo yeziguli zaseShayina ezine-MR eqinile. Inkolelo ye-Peijia Medical “yokubeka ukuphila kweziguli nokuphepha kuqala ngokuthuthukisa ukuthuthukiswa kwezindlela zokwelapha ezihlaselayo ekhaya nasemazweni angaphandle” ayikaze ishintshe.