I-Metformin Eye Drops yokwelashwa kwe-Macular Degeneration

I-Curative Biotechnology, Inc. imemezele namuhla ukuthi inkampani isithuthukele ocwaningweni lwayo lwe-Good Laboratory Practice (GLP) lwe-toxicology.

Ucwaningo lwamanje lwenzelwe ukukala ukubekezelelana, i-pharmacokinetics kanye nanoma yibuphi ubuthi bendawo noma besistimu be-metformin elungisiwe lapho kulawulwa ukulethwa kwe-topical ocular. Ucwaningo luzophinde luhlole ukusatshalaliswa kwalo kwezicubu ze-ocular.

Ucwaningo lwe-Good Laboratory Practice (GLP) luyisidingo sokugcwaliswa kwe-FDA Investigational New Drug (IND).

Ukubekezelela amehlo kuhlanganisa ukubhekwa lapho kufakwa umthamo, ukubhekwa komtholampilo okuvamile kabili nsuku zonke (ukuhlolwa kokuziphatha/izimpawu zomtholampilo okunakwa ngokukhethekile amehlo), ukuhlolwa kwamehlo okwenziwa udokotela wamehlo wezilwane ogunyazwe yiBhodi ngokwesilinganiso samagoli se-Hackett-McDonald esishintshiwe, kanye ne-ocular histopathology. .

Ngaphansi kwe-Cooperative Research and Development Agreement (CRADA), i-National Eye Institute (NEI) kanye ne-Curative Biotechnology, Inc. izosebenzisana ukuze ihlole ukwakheka kwe-Curative's ocular ocular metformin ezifundweni zemitholampilo ukuze zelashwe ukuwohloka kwe-Macular okuhlobene nobudala okumaphakathi nesemuva kwesikhathi. (AMD) isifo.