I-COVID ende: Inkinga Yezempilo Entsha?

I-BioWorld eshicilelwe ngabakwaClarivate Plc, umholi womhlaba wonke ekunikezeni ulwazi nemininingwane ukuze kusheshiswe ijubane lokuqamba izinto ezintsha, umemezele ukuhlaziya okusha okulandela intuthuko yakamuva ehlobene nocwaningo lwe-COVID-19 ende, isifo esiyinkimbinkimbi esithinta abantu abangaphezu kwezigidi eziyi-100 emhlabeni jikelele. I-BioWorld iwuchungechunge lwezinsizakalo zezindaba eziwine umklomelo eziletha ubuhlakani obuphathekayo ekwelapheni okusha kakhulu kanye nobuchwepheshe bezokwelapha obuthuthukiswayo. Ukuhlaziywa kungena ocwaningweni lwakamuva olusebenza ukuchaza lesi sifo - okungenzeka kube inkinga yezempilo yomphakathi edonsa isikhathi eside - futhi kuhlaziya izifundo ezingaphezu kwama-40 zokwelashwa okungaba khona kwe-COVID ende.

Ososayensi ekuqaleni baqala ukufunda i-post-acute COVID-19 syndrome, eyaziwa nangokuthi i-COVID ende, ngo-Agasti 2020. Kuso sonke lesi sifo, imboni ye-biopharmaceutical ibilokhu igxile ekuletheni imigomo ye-COVID-19 kanye nokwelapha ezigulini ezinejubane eleqile, okuphawulekayo “okokuqala,” okuhlanganisa nomgomo wokuqala we-DNA. Kodwa-ke, ukwelashwa kwesimo esiqhamukayo kuhlala kungenakwenzeka. Manje, cishe iminyaka emibili kulo bhubhane lomhlaba wonke, izinkulungwane zabantu zibamba iqhaza ezifundweni ukuze zisize ukuqonda kangcono isici esivame ukuqondwa kabi se-COVID-19.

Ithimba le-BioWorld libuyekeze futhi lahlaziya izifundo eziningi ezibuyekezwe ontanga ezihlose ukuthola incazelo yokuqala yocwaningo yalokho okushiwo yi-COVID ende, efana nalokho okuphakanyiswe yi-World Health Organization. Incazelo yocwaningo ihloselwe ukulinganisa ukuqoqwa kwedatha nendlela yokusebenza, ingasetshenziselwa ukuxilonga iziguli kanye nokuhlinzeka ngokufinyelela ekunakekelweni kwezokwelapha. Ukuhlaziywa kwe-BioWorld kuchaza ukuthuthukiswa kwale ncazelo esekelwe ekuvumelaneni ye-COVID-19 ende, izimpawu kanye nezibikezelo ezingaba khona zokuthi ubani ozophathwa yileso simo. Isebenzisa idatha nemininingwane evela ku-BioWorld, Cortellis, kanye ne-clinicaltrials.gov, ithimba liphinde lahlaziya izindlela zokwelapha ezingaba khona ekuthuthukisweni ukwelapha lesi sifo kuyilapho ngesikhathi esifanayo libuza: Zingaba khona kanjani izindlela zokwelapha uma singenayo ngisho nencazelo yokugcina yokuvumelana? Kuze kube manje, ithimba lilandelela izidakamizwa ezingama-41 esakhiwayo, ngemithathu nje esesigabeni sokuhlola.

Bebonke, abacwaningi bafuna izikhathi ezimisiwe zezifo kanye nezimpawu ezisebangeni lobudala, ubulili kanye nezindawo. Izidakamizwa ezihlolwayo zifaka phakathi ukuhogela, i-intranasal, intravenous, ngomlomo kanye nezinguqulo ze-rectal zemithi, okuhlanganisa izidakamizwa ezilwa namagciwane, ama-stem cells, biologics, i-naltrexone, i-anti-inflammatories, ama-statins, ama-antibiotics, ama-antioxidants, i-remdesivir kanye nama-bodyized monoclonal antibodies.

ULynn Yoffee, Umshicileli, i-BioWorld uthe: “Kuze kube manje, siyazi ukuthi kunezimpawu eziyi-19 ezihlobene nalesi sifo ezisukela ekukhathaleni isikhathi eside kuya ekuhlulekeni kwezitho eziningi. Ngakho-ke, lokhu kungaphezu nje kwesifo sokuphefumula. Umthelela emphakathini ungaba mkhulu ngoba asazi ukuthi abantu bazoqhubeka isikhathi eside kangakanani nalesi sifo, esisachazwa namanje. I-BioWorld manje ilandelela izifundo ezingu-41 zemithi yokwelapha engaba khona ekuthuthukisweni. Lolo uhlu olufushane oluqhathaniswa nemithi engama-787 esathuthukiswayo yokwelapha isifo esisebenzayo. Kodwa kuyaqondakala, ngoba abacwaningi basabhekana nencazelo eqinile yesifo kanye nezibalo ezikhomba ngokuphelele inani leziguli.”