I-Sensory Cloud imemezele namuhla okutholwe okusha kocwaningo lomtholampilo okwenziwa yithimba lamazwe ngamazwe lososayensi e-Bangalore Baptist Hospital, e-Harvard University, Massachusetts General Hospital, Research Triangle Institute, University Leicester, GS BIO-INHALATION kanye ne-Sensory Cloud Inc. eshicilelwe ku-Scientific Reports ebonisa indlela yomoya. inhlanzeko enosawoti ocebile we-calcium hypertonic (FEND) kunciphisa izimpawu ze-COVID-19.
Ucwaningo luhlole ukuthi izimpawu ze-COVID-19 zathintwa kanjani ukugeleza kwemigudu yomoya ephezulu. Okutholakele kukhombisa ukuthi ngenkathi ukukhiqizwa kwamaconsi okuphefumula kukhuphuka ngama-oda angu-4 obukhulu ezifundeni eziphelelwe amanzi emzimbeni ubudala, ubudala obuphezulu be-BMI, ukuvivinya umzimba okukhandlayo, kanye nokutheleleka kwe-SARS-CoV-2, ukugeleza kwamanzi okuhlosiwe kwekhala, i-larynx kanye noqhoqhoqho. usawoti we-calcium-rich hypertonic (FEND) ezigulini ezine-COVID-19 wehlisa ukukhiqizwa kwamaconsi okuphefumula, ukhuphula ukugcwala komoyampilo futhi unciphise izimpawu zesifo ngokuhlobene nokulawula usawoti wamakhala.
Lokhu okutholakele ocwaningweni olusha kukhombisa ukuthi ukufakwa kwe-hydration kwemigwaqo yomoya ephezulu kubonakala kuthembisa njengendlela engeyona eyezidakamizwa yokunciphisa ubungozi bezifo zokuphefumula njenge-COVID-19.
"Kuqondakala kahle ukuthi ukuphefumula komoya owomile kwandisa ubungozi bezifo zokuphefumula kusukela kusifuba somoya kuya ku-COVID-19," kusho uCarol Elizabeth George, MD, umbhali wokuqala we-athikili yaseBangalore Baptist Hospital. “Ucwaningo oluningi luphinde lwaveza izinzuzo zezempilo zokuphefumula zokuphefumula umoya ohlanzekile onomswakama. Ezweni elinomoya ongcolile nowomile, ikhono lokunikeza izinzuzo ze-airway hydration nge-hygienic rite elula njengokuphefumula kwamanzi anosawoti acebile nge-calcium kathathu ngosuku kunokunakekelwa okukhethekile kwezempilo emiphakathini efana naleyo engiyinakekelayo, lapho akukho lutho olutholakala emithini, imigomo nenhlanzeko eyisisekelo, nalapho isifo sokuphefumula siyimbangela eyinhloko yokufa nokugula.”
"Sihlonishwa ngokusebenza nabantu abangavamile njengoDkt. Carol Elizabeth George, mina nabanye abasebenzi bezempilo nososayensi, ukuhlola lolu hlobo olusha lwenhlanzeko olubhekiswe emigwaqweni ephezulu yomoya ngosawoti we-hypertonic," kusho uDkt. Dennis Ausiello, uMqondisi we-CATCH, I-Massachusetts General Hospital, uJackson Ohlonishwayo onguProfesa Wezokwelapha Ezokwelapha e-Harvard Medical School.
Ocwaningweni olufana nolwemitholampilo olubikwe ngababhali obelugxile ekuphelelweni amanzi emzimbeni okudalwe wukuzivocavoca, i-aerosol ekhishwe umoya yanda cishe izikhathi eziyi-15 kulandela ihora elilodwa lokuzivocavoca (phakathi kuka-0.5 kuya ku-1.0% ukulahlekelwa kwesisindo somzimba wonke); lokhu okutholakele okusha kukhomba isici esasingaziwa ngaphambili esingase sibe nomthelela ekubhebhethekeni kwe-COVID-19 ezimeni zokusubatha kanye nengozi ephakeme yokugula okungenwa yizifo zokuphefumula phakathi kwabasubathi abakhuthazela kakhulu.
"Ama-saline emakhaleni abonakale ezuzisa izinkulungwane zeminyaka njengendlela yokuhlanza amafinyila emakhaleni," kusho umlobi okhulumayo uDkt. David Edwards, UProfesa wase-Harvard University we-Practice of Bioengineering (2002-2019), kanye nomsunguli we-FEND. "Sithola ukuthi ukufaka amanzi kumphimbo noqhoqhoqho kunikeza umthelela omkhulu ekuhlanzekeni kokuphefumula, njengoba ukuphuma komzila womoya ophezulu kanye nokusebenza komoyampilo kulawulwa kakhulu i-larynx egcwele amanzi kanye noqhoqhoqho."
Lolu cwaningo olusha lukhanyisa umthelela wokuphelelwa amanzi emzimbeni wonke, okuvamise ukuhambisana ne-COVID-19 futhi kuyisici esivamile esingaba khona ezifundeni ze-phenotypical ezifana nokuguga kanye ne-BMI ephezulu ehambisana nengozi eyandayo yesifo.
LOKHO ONGAKUTHATHE KULESI SIHLOKO:
- In a world of dirty and dry air, the ability to confer the benefits of airway hydration with a hygienic rite as simple as the breathing of calcium-rich salt water three times a day has special healthcare relevance to communities like those I care for, where there is hardly any access to drugs, vaccines and basic hygiene, and where respiratory disease is the principal cause of death and morbidity.
- The findings show that while respiratory droplet generation increases by up to 4 orders of magnitude in dehydrated associated states of advanced age, elevated BMI-age, strenuous exercise, and SARS-CoV-2 infection, targeted hydration of the nose, larynx and trachea with calcium-rich hypertonic salts (FEND) in COVID-19 positive patients decreases respiratory droplet generation, increases oxygen saturation and reduces symptoms of disease relative to a nasal saline control.
- Lolu cwaningo olusha lukhanyisa umthelela wokuphelelwa amanzi emzimbeni wonke, okuvamise ukuhambisana ne-COVID-19 futhi kuyisici esivamile esingaba khona ezifundeni ze-phenotypical ezifana nokuguga kanye ne-BMI ephezulu ehambisana nengozi eyandayo yesifo.
