I-SciSparc Ltd., inkampani yezokwelapha egxile ekuthuthukisweni kwemithi yokwelapha ukuphazamiseka kwesimiso sezinzwa esiyinhloko, namuhla imemezele ukwakhiwa okuhlosiwe kwe-joint venture (“JV”) ukuze kugxilwe ekutholakaleni nasekuthuthukisweni kwamakhono angenzeka. izidakamizwa zomdlavuza nezinye izimo ezibeka impilo engozini. Ngaphansi kwemigomo ye-JV, ukukhuthaza le nhloso, i-SciSparc izosungula inkampani entsha yokutholwa kwezidakamizwa, i-MitoCareX Bio Ltd., inhlangano yakwa-Israel (“MitoCareX Bio”).
I-JV izogxila ekuphenyeni abathwali be-mitochondrial, amaprotheni ezokuthutha abalulekile ekusebenzeni kwamaseli. Ngenxa yendima ebalulekile yabathwali be-mitochondrial ekuhambiseni ama-metabolite adingekayo ukuze asebenze kweseli kulwelwesi lwangaphakathi lwe-mitochondrial, Inkampani ikholelwa ukuthi izimo ezihlukahlukene ezisongela ukuphila, ezifana nomdlavuza nezifo ezingavamile ze-mitochondrial, zingelashwa ngokulawula umsebenzi wabathwali be-mitochondrial. Kubantu, umndeni othwala i-mitochondrial (Solute Carrier Family 25, SLC25) unamalungu angama-53 futhi uwumndeni omkhulu we-solute transporter.
"Leli yithuba elijabulisayo lokwandisa ipayipi lethu libe yizinkomba ezintsha eziningi eziqondise izidingo ezinkulu zezokwelapha ezingahlangatshezwana nazo," kusho u-Oz Adler, oyiChief Executive Officer kanye neChief Financial Officer ye-SciSparc. "I-MitoCareX Bio ihlose ukusebenzisa amakhono okutholwa kwezidakamizwa asekelwe kukhompyutha, isebenzise ulwazi oluningi locwaningo nolwazi oluthile kulo mkhakha, ukuthola kanye nethuba lokuthuthukisa ipayipi elingase lihlanganise ama-molecule amancane aqondise amaprotheni anentshisekelo ezimweni ezihlukahlukene ezisongela ukuphila."
Ukwakha i-JV, i-SciSparc izosungula inkampani entsha yokutholwa kwezidakamizwa, i-MitoCareX Bio Ltd. (“MitoCareX Bio”). Ngokusekelwe ezinyathelweni ezinqunywe kusengaphambili, i-SciSparc izotshala imali efika ku-$1.7 million, kuze kufike kumaphesenti angu-50.01 ubunikazi, ku-MitoCareX Bio phakathi neminyaka emibili ezayo futhi ngokuvumelana nenani lezinyathelo okuvunyelwene ngazo esivumelwaneni. Ucwaningo olusha lwe-MitoCareX Bio ngokwengxenye luzokwakhela phezu kokuhlolwa okuyimpumelelo kobufakazi bomqondo okwenziwe e-UK. USolwazi Ciro Leonardo Pierri (University of Bari, Italy), uchwepheshe womhlaba wonke emkhakheni we-mitochondrial carrier proteins, uveze eNkampanini ukuthi uhlose ukweseka lolu hlelo njengomeluleki weNkampani.
