Ukuhlolwa Okusheshayo Kwe-COVID-19 Ukufundwa eFinland

Phakathi kocwaningo lomuthi wokugoma wokulwa ne- I-COVID-19 coronavirus ifunwa amazwe angaba ngu-30, iFinland yazisa ngesigaba sayo sokuqhubeka kokuhlolwa okusheshayo kwamadivayisi e-COVID-19 ukukhomba igciwane eliyingozi. Lokhu kubikwe nguMnu. Gianfranco Nitti, intatheli yephephandaba lansuku zonke laseFinland “La Rondine” nelungu le-Foreign Media Associatio, eRome. Umbiko uthi:

Ukwenza izivivinyo ezisheshayo futhi ezinokwethenjelwa ukukhomba lesi sifo esiwumshayabhuqe seminyaka yethu eyinkulungwane esigabeni saso sokuqala ukuzibophezela kwamalabhorethri, ososayensi nezikhungo zocwaningo emhlabeni wonke. Lokhu yilokho okwaphakanyiswa eFinland e I-VTT, Isikhungo Sombuso Sokucwaninga, Ukuthuthukiswa Nokusungula.

Ngabasebenzi abangaphezu kuka-2,000 1942, kufaka phakathi inani elikhulu lososayensi nabaphenyi, kukhuthaza ukukhula okusimeme futhi kubhekane nezinselelo ezinkulu zomhlaba zesikhathi sethu ukuziguqula zibe ngamathuba okukhula, kusiza umphakathi nezinkampani ukuthi zikhule ngokusebenzisa ubuchwepheshe obusha. Isungulwe ku-80, inamava acishe abe yi-XNUMX yeminyaka ocwaningweni oluphakeme nakwimiphumela yesayensi.

Ithimba labaphenyi be-MeVac

Futhi kwakuyi-VTT kuphela lapho umsebenzi waqala ngohlobo olusha lokuhlola olususelwa ekutholeni ama-antigen egciwane egciwane le-COVID-19. Inhloso yokuhlolwa okusheshayo ukuhlinzeka ochwepheshe bezokunakekelwa kwempilo ngendlela enembile, esheshayo neyonga izinsiza ukuze kutholakale kusenesikhathi ukutheleleka kwe-coronavirus ngokuhlolwa okusheshayo kwe-COVID-19.

Ukuthuthukiswa kokuhlolwa okusheshayo kwenziwa yi-VTT kanye nesikhungo sokucwaninga se-MeVac - Meilahti somuthi wokugoma. Le phrojekthi futhi ifuna ngentshiseko izinkampani zaseFinland ukuthi zijoyine ukubambisana.

Indlela yokuhlola esheshayo isuselwa ekutholeni ama-antigen egciwane kumasampula we-nasopharyngeal futhi izovumela ukutholakala kwe-COVID-19 kusenesikhathi sokuqala kwesifo. Ukuhlolwa kuklanyelwe ukwenziwa ochwepheshe bezokunakekelwa kwezempilo - okungenani esigabeni sokuqala. Kodwa-ke, imiphumela izobuyiselwa ngokushesha okukhulu kunezivivinyo ezikhona, kungakapheli imizuzu engu-15 noma ngaphansi.

I-prototype yethuluzi lokuxilongwa ngokushesha

Ukuhlolwa okusha okusheshayo kwe-COVID-19 nakho kungabiza kakhulu kunezindlela zamanje zokuhlola. Ukuthuthukiswa kwama-antibody sekuqalile e-VTT futhi izinhlobo zokuqala zohlolo kulindeleke ekwindla ka-2020.

“Njengoba isimo esiwubhadane siba sibi emazweni omhlaba, sesiqalile ukufuna izixazululo endaweni yethu yokwenza kahle kakhulu. Sinolwazi lokwakha nokukhiqiza ama-antibodies, kanye nesipiliyoni sangaphambilini ekwakhiweni kwezivivinyo zokuxilonga. Kwakuyisinqumo esilula kithi ukuthi siqale ukusebenza nge-antibody ye-COVID-19, ”kusho uDkt Leena Hakalahti, umholi wethimba locwaningo lwe-VTT biosensor.

Ucwaningo olwenziwe ngu-HUS Helsinki, isibhedlela saseyunivesithi, lubamba iqhaza elibalulekile ekwakheni amasosha omzimba futhi amasampula asetshenziswe ocwaningweni athathwe ezigulini ezazinokutheleleka nge-coronavirus.

Le phrojekthi yenziwa ngokubambisana okukhulu namathimba ocwaningo aholwa nguprofesa we-virology e-University of Helsinki, u-Olli Vapalahti kanye nomqondisi weMeVac Vaccine Research Center, uprofesa wezifo ezithathelwanayo kuleyunivesithi efanayo, i-Anu Kantele.

“Njengoba ucwaningo luqhubeka, sizohlola ukuthi kungenzeka yini ukuthi kusetshenziswe ama-antibody athuthukisiwe hhayi nje kuphela ukuhlolwa kepha nasekwelapheni isifo se-coronavirus,” kusho uProfesa Vapalahti.

I-VTT isiqalile ucwaningo lokwakha amasosha omzimba amasha alwa nama-antigen wegciwane le-SARS-CoV-2 ngezimali zangaphakathi, kepha iphrojekthi manje ifuna ngokucophelela imali eyengeziwe kanye nabalingani bokuthuthukiswa kokuhlolwa okusheshayo kwalokhu kuhlolwa okusheshayo kwe-COVID-19. Ukukhiqizwa kwezivivinyo nemishini yabo yokuhlaziya kungenziwa eFinland yizinkampani ze-VTT nezaseFinland futhi, ngaphezu kokuhlangabezana nezidingo zangaphakathi, kungathengiswa umhlaba wonke.

“Ukwandisa ikhono lokwenza isivivinyo kudlala indima enkulu ekuqapheleni ukuqhubeka kwalo bhubhane, kodwa izindlela zamanje zokuhlola zidinga isikhathi esiningi nezinsizakusebenza ezinciphisa amandla.

Inhloso yokuhlolwa okusheshayo ukuvumela ukukhula kwamandla okuhlola nokuqinisekisa ukutholakala kwezivivinyo noma ngabe ubhadane lusaqhubeka, "kuphawula usekela mongameli wendawo yocwaningo, uDkt. Jussi Paakkari we-VTT.

Sebenza esivivinyweni esisheshayo manje sigxile ngqo ku-COVID-19, kepha uma lokhu kuchazwa okusheshayo kobuchwepheshe be-COVID-19 kuchazwa, inqubo efanayo yokuthuthuka ingasetshenziswa ngokushesha ukuxilonga amanye amagciwane.

Ukuxilongwa kanye nempilo yedijithali yizindawo eziyinhloko zobuchwepheshe be-VTT enabantu abangaba ngu-80 abasebenza ngezihloko ezihlobene eFinland ezikhungweni zase-Oulu, Espoo, Tampere naseKuopio. I-VTT futhi inolwazi oluningi ekuklanyweni kwamathuluzi wokuhlonza enzelwe izifo ezahlukahlukene.

Iphothifoliyo yezobuchwepheshe ye-VTT ifaka konke okudingekayo ukuthuthukisa amathuluzi nezinhlelo zokulahla ezilahlwayo; isikhungo sikwazi ukuhlanganisa ubuchwepheshe kuma-antibodies nokukhiqizwa kochungechunge lwemichilo yokuhlola nokuhlaziywa kwedatha okunembile.