Ucwaningo olusha lomtholampilo ekwelashweni kwedijithali kokukhathazeka

I-Vicore Pharma Holding AB namuhla imemezela isiguli sokuqala esibhalise esigabeni sokuhlola se-COMPANION1, isifundo somtholampilo sokwelashwa kokuziphatha kwengqondo okudijithali kweziguli ezine-IPF.

Iziguli ezine-IPF zinesikhathi sokuphila iminyaka emithathu kuya kwemihlanu, lapho i-dyspnea, ukukhathala nokukhwehlela kuba kubi kancane kancane futhi ocwaningweni olwandulelayo, kwaboniswa ukuthi i-63% yeziguli ze-IPF zibika izinga eliphakathi nendawo lokukhathazeka2. I-Cognitive Behavioral therapy (CBT) iyindlela esungulwe kahle yokusiza iziguli ezinomthwalo ongokwengqondo obangelwa isifo esinzima futhi i-CBT yedijithali inenzuzo yokufinyeleleka ubusuku nemini futhi ingenziwa ibe ngeyakho ukuze ihlangabezane nezidingo zesiguli.

I-COMPANION iwucwaningo lomtholampilo olufakwe kudijithali ngokugcwele, olungahleliwe, olulawulwa ngokuhambisana ukuze kuhlolwe umthelela wokwelashwa kwedijithali i-Almee™ emthwalweni wezimpawu ezingokwengqondo kubantu abadala abatholakala bene-IPF. Ucwaningo lwe-COMPANION luqukethe izigaba ezimbili; ucwaningo lokuhlola oludizayinelwe ukucolisa isimo sokusebenzisana seseshini yokwelapha, okulandelwa ucwaningo olubalulekile. Ucwaningo luzokwenzeka e-US futhi kulindeleke ukuthi luphothulwe ngo-H1 2023, ngemva kwalokho i-Vicore izofuna imvume ye-FDA ye-Almee™ njengethuluzi lezokwelapha futhi kulindeleke ukuthi itholakale ezigulini ngo-2024. I-Almee™ ithuthukiswa ngokubambisana no I-Alex Therapeutics AB* kanye nocwaningo lwe-COMPANION lwenziwa kusetshenziswa izixazululo ezingokoqobo zomtholampilo ezakhiwe yi-Curebase Inc*.

“Sijabule kakhulu ngokwenza isiguli sethu sokuqala ngokungahleliwe esigabeni sokuhlola socwaningo lwe-COMPANION. Lolu cwaningo ngeke lusize kuphela ekucaciseni umphumela wokukhathazeka eqophelweni lempilo yeziguli ze-IPF, luzophinde luhlole nezinzuzo zokwelapha ezisezingeni eliphezulu,” kusho uSolwazi Maureen Horton, umphenyi oyinhloko we-COMPANION, i-Johns Hopkins University.

“I-Almee™ iyingxenye ebalulekile yesu lokuthuthukisa i-Vicore lokwelashwa okuphelele nokuqondene nomuntu siqu kwesifo samaphaphu esingavamile futhi ibhekana nesidingo esicacile esingafezeki eqenjini leziguli ze-IPF. Lolu cwaningo lomtholampilo oluhlukaniselwe futhi lusinika ithuba lokucabanga kabusha ngemodeli yesilingo somtholampilo esijwayelekile sibe sigcina isiguli sigxile,” kusho uJessica Shull, uMqondisi weDigital Therapeutics e-Vicore.